Aaron and Jordan’s paper is accepted for publication in Int J Numer Method Biomed Eng
The paper by group alumnus Aaron Barrett, along with Jordan Brown, A model of fluid–structure and biochemical interactions for applications to subclinical leaflet thrombosis, has been accepted to appear in International Journal for Numerical Methods in Biomedical Engineering. This study was also done in collaboration with John Vavalle at UNC, Arash Kheradvar at UC Irvine, and Aaron Fogelson at the University of Utah.
Congratulations, Aaron and Jordan!
David and Ben’s paper is accepted for publication in J Comput Phys
David Wells and Ben Vadala-Roth’s paper, which was also written with Mike Lee and is entitled, A nodal immersed finite element-finite difference method, has been accepted to appear in Journal of Computational Physics.
Congratulations, David, Ben, and Mike!
Jordan’s paper is accepted for publication in Ann Biomed Eng
Jordan Brown’s paper, Patient–Specific Immersed Finite Element–Difference Model of Transcatheter Aortic Valve Replacement, has been accepted to appear in Annals of Biomedical Engineering in their Special Issue on Modeling for Advancing Regulatory Science.
Congratulations, Jordan!
Simone and Laryssa’s paper is accepted for publication in Front Physiol
Simone Rossi and Laryssa Abdala’s paper, Rule-based definition of muscle bundles in patient-specific models of the left atrium, has been accepted to appear in Frontiers in Physiology.
Congratulations, Simone and Laryssa!
Mike’s paper is accepted for publication in J Comput Phys
Mike Lee’s paper, On the Lagrangian-Eulerian coupling in the immersed finite element/difference method, has been accepted to appear in Journal of Computational Physics. (A preprint is available on the arXiv.) This paper systematically tests the accuracy of the immersed finite element/difference method (IBFEMethod in IBAMR) using different regularized delta functions and relative mesh densities for several benchmark problems along with our large-scale model of a bioprosthetic heart valve in a pulse duplicator. Our results indicate that kernels satisfying a commonly imposed even–odd condition require higher resolution to achieve similar accuracy as kernels that do not satisfy this condition. We also find that narrower kernels are more robust, in the sense that they yield results that are less sensitive to relative changes in the Eulerian and Lagrangian mesh spacings, and that structural meshes that are substantially coarser than the Cartesian grid can yield high accuracy for shear-dominated cases but not for cases with large normal forces. I think this will be a very useful study for practitioners of the IB method.
Congratulations, Mike!
New NIH award on leaflet thrombosis in bioprosthetic heart valves
We are thrilled to announce that we just received notification of a new $2.7M NIH R01 award for a project that aims to create and use experimentally and clinically validated computer models to understand the mechanisms that lead to subclinical leaflet thrombosis in bioprosthetic heart valves following aortic valve replacement, and thereby improve risk stratification and device selection for patients who require aortic valve replacement to treat aortic stenosis.
This is a collaborative project that will be carried out with teams of researchers at the University of California, Irvine (PI: Arash Kheradvar) and the University of Utah (PI: Aaron Fogelson) along with collaborators here at UNC School of Medicine.
Kirsten is awarded an American Heart Association Predoctoral Fellowship
Kirsten Giesbrecht has been awarded an American Heart Association Predoctoral Fellowship for 2022-2024!
Aaron’s paper is accepted for publication in J Comput Phys
Aaron Barrett’s paper, A hybrid semi-Lagrangian cut cell method for advection-diffusion problems with Robin boundary conditions in moving domains, has been accepted to appear in Journal of Computational Physics. (A preprint is available on the arXiv.) This paper introduces a new discretization approach to advection-diffusion equations with Robin boundary conditions on complex time-dependent domains. This work is part of broader efforts to simulate thrombosis in atrial fibrillation and leaflet thrombosis following aortic heart valve replacement.
Congratulations, Aaron!
Congratulations Dr. Robert Hunt!
Congratulations to Robert Hunt for successfully completing his PhD.
Robert’s thesis is entitled, Part I: Diffusion-Induced Flows and Particulate Aggregation. Part II: Experiments and Modeling of Replacement Aortic Valves. Part III: Enhanced Diffusion in Wall-driven Shear Flows. Robert is off to a postdoctoral position at Brown University’s School of Engineering.
Good luck, Robert!
Bryn is awarded a DOE Computational Science Graduate Fellowship
Bryn Barker has been selected to the 2021-2022 incoming class of DOE Computational Graduate Fellowship program. (For more information about this program, see the announcement from the Krell Institute.)
Congratulations, Bryn!!