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We are trilled to announce that we just received notification of a new $2.7M NIH R01 award for a project that aims to create and use experimentally and clinically validated computer models to understand the mechanisms that lead to subclinical leaflet thrombosis in bioprosthetic heart valves following aortic valve replacement, and thereby improve risk stratification and device selection for patients who require aortic valve replacement to treat aortic stenosis.

This is a collaborative project that will be carried out with teams of researchers at the University of California, Irvine (PI: Arash Kheradvar) and the University of Utah (PI: Aaron Fogelson) along with collaborators here at UNC School of Medicine.

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